![]() Also, we will describe the imaging discriminators of potential mimickers of PDAC. For each category, the key imaging features and potential pitfalls on cross-sectional imaging will be discussed. These include radiological and clinical subtleties of the tumor, evolving imaging criteria for tumor resectability, preoperative diagnosis of accompanying celiac artery stenosis, and post-neoadjuvant therapy imaging. In this review, we discuss the challenges related to the imaging of PDAC. Coexistent celiac artery stenosis may affect the surgical plan in patients undergoing pancreaticoduodenectomy. ![]() Tumor resectability and its contingency on the vascular invasion most commonly assessed with multi-phasic thin-slice CT is a continuously changing concept, particularly in the era of frequent neoadjuvant therapy. Early PDAC can be missed on CT due to similar attenuation relative to the normal pancreas, small size, or hidden location in the uncinate process. Pancreatic ductal adenocarcinoma (PDAC) has continued to have a poor prognosis for the last few decades in spite of recent advances in different imaging modalities mainly due to difficulty in early diagnosis and aggressive biological behavior.
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